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Whole-exome Sequencing Reveals New Potential Susceptibility Genes for Japanese Familial Pancreatic Cancer.

Annals of surgery - 1 Apr 2022

Takai Erina, Nakamura Hiromi, Chiku Suenori, Kubo Emi, Ohmoto Akihiro, Totoki Yasushi, Shibata Tatsuhiro, Higuchi Ryota, Yamamoto Masakazu, Furuse Junji, Shimizu Kyoko, Takahashi Hideaki, Morizane Chigusa, Furukawa Toru, Yachida Shinichi

Abstract excerpt

OBJECTIVE: The primary objective of this study was to identify novel genes that predispose people in the Japanese population to FPC. SUMMARY OF BACKGROUND DATA: Familial history of pancreatic cancer is an important risk factor but, to date, few genes predisposing individuals to increased risk of developing FPC have been identified. METHODS: We performed whole-exome sequencing of germline DNA from 81 Japanese FPC...

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PMID: 32826389
DOI: 10.1097/SLA.0000000000004213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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