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Mutations in Known and Novel cancer Susceptibility Genes in Young Patients with Pancreatic Cancer.

Archives of Iranian medicine - 1 Jun 2018

Alimirzaie Sahar, Mohamadkhani Ashraf, Masoudi Sahar, Sellars Erin, Boffetta Paolo, Malekzadeh Reza, Akbari Mohammad R, Pourshams Akram

Abstract excerpt

BACKGROUND: Pancreatic cancer is the fourth most common cause of mortality due to cancer, globally. It has a poor prognosis and is usually diagnosed at later stages when tumor resection is not possible. Heritability for pancreatic cancer is relatively high and clinically significant. METHODS: A group of 24 pancreatic cancer patients with young age at onset, from a referral hospital in Tehran University of Medical...

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Identifiers

PMID: 29940740

Genes

BRCA1
EXO1
PARP4

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