Article
Absence of methamphetamine-induced conditioned place preference in weaver mutant mice.
Neuropsychopharmacology reports - 1 Dec 2020
Ikekubo Yuiko, Ide Soichiro, Hagino Yoko, Ikeda Kazutaka
Abstract excerpt
AIMS: G protein-activated inwardly rectifying potassium (GIRK) channels are related to rewarding effects of addictive drugs. The GIRK2 subunit is thought to play key roles in the reward system. Weaver mutant mice exhibit abnormal GIRK2 function and different behaviors that are caused by several addictive substances compared with wild-type mice. However, mechanisms of reward-related alterations in weaver mutant...
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