Article
Role of convergent activation of glutamatergic and dopaminergic systems in the nucleus accumbens in the development of methamphetamine psychosis and dependence.
The international journal of neuropsychopharmacology - 1 Jul 2013
Miyazaki Masayuki, Noda Yukihiro, Mouri Akihiro, Kobayashi Kazuto, Mishina Masayoshi, Nabeshima Toshitaka, Yamada Kiyofumi
Abstract excerpt
Methamphetamine (Meth) abuse can result in long-lasting psychosis and dependence. The nucleus accumbens (NAc), which controls psychomotor and reward behaviours, is an important interface between the limbic system and receives convergent projections from dopaminergic and glutamatergic terminals. This study investigated the involvements of dopaminergic and glutamatergic transmission in the development of Meth...
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