Article
Gene expression differences in mice divergently selected for methamphetamine sensitivity.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 2005
Palmer Abraham A, Verbitsky Miguel, Suresh Rathi, Kamens Helen M, Reed Cheryl L, Li Na, Burkhart-Kasch Sue, McKinnon Carrie S, Belknap John K, Gilliam T Conrad, Phillips Tamara J
Abstract excerpt
In an effort to identify genes that may be important for drug-abuse liability, we mapped behavioral quantitative trait loci (bQTL) for sensitivity to the locomotor stimulant effect of methamphetamine (MA) using two mouse lines that were selectively bred for high MA-induced activity (HMACT) or low MA-induced activity (LMACT). We then examined gene expression differences between these lines in the nucleus...
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