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Article

Hnrnph1 is a novel regulator of alcohol reward.

Drug and alcohol dependence - 1 Mar 2021

Fultz Elissa K, Coelho Michal A, Lieberman Dylan, Jimenez-Chavez C Leonardo, Bryant Camron D, Szumlinski Karen K

Abstract excerpt

BACKGROUND: Hnrnph1 is a validated quantitative trait gene for methamphetamine behavioral sensitivity that encodes for heterogeneous nuclear ribonucleoprotein H1 (hnRNP H1). This RNA-binding protein is involved in all stages of RNA metabolism that impacts mesocorticolimbic dopamine neurotransmission to influence addiction-related behavior. METHODS: We characterized the alcohol behavioral phenotypes of mice...

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Identifiers

PMID: 33454624
DOI: 10.1016/j.drugalcdep.2021.108518
PMCID: PMC7899125

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