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Article

The role of competing mechanisms on Lck regulation.

Immunologic research - 1 Oct 2020

Bozso Sabin J, Kang Jimmy J H, Nagendran Jeevan

Abstract excerpt

Lck is a Src-related protein tyrosine kinase that associates with CD4 and CD8 molecules and is essential to T cell development and T cell activation. Regulatory mechanisms of Lck are diverse and controversy exists regarding the importance of each mechanism. The balance of phosphorylation at the inhibitory and activating Tyr residues is maintained by a balance between CD45 and Csk and is dependent upon intact...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymphocyte Specific Protein Tyrosine Kinase p56(lck)

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Source

Identifiers

PMID: 32794043
DOI: 10.1007/s12026-020-09148-2

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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