Back to search

Article

Control of T lymphocyte fate decisions by PI3K signaling

2020-09-25

Abstract excerpt

Virtually all aspects of T and B lymphocyte development, homeostasis, activation, and effector function are impacted by the interaction of their clonally distributed antigen receptors with antigens encountered in their respective environments. Antigen receptors mediate their effects by modulating intracellular signaling pathways that ultimately impinge on the cytoskeleton, bioenergetic pathways, transcription, and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2ec022e3-8911-544d-807b-ab64f120c309
DOI
10.12688/f1000research.26928.1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Control of T lymphocyte fate decisions by PI3K signalingDOI 10.12688/f1000research.26928.1
Role of class IA phosphoinositide 3-kinase in B lymphocyte development and functions.Semantic proximity
P <scp>hosphoinositide</scp> 3-K <scp>inase</scp> : Diverse Roles in Immune Cell ActivationSemantic proximity
T cell receptor (TCR) signaling in health and diseaseSemantic proximity
The role of PTEN as a PI(3,4)P2 lipid phosphatase in Class I phosphoinositide 3-kinase signallingSemantic proximity
The role of PI3Kγ in the immune system: new insights and translational implicationsSemantic proximity
The cell biology behind the oncogenic PIP3 lipidsSemantic proximity
The role of PLCγ2 in immunological disorders, cancer, and neurodegenerationSemantic proximity
Towards an understanding of isoform specificity in phosphoinositide 3-kinase signalling in lymphocytes.Semantic proximity
Homeostatic and pathogenic roles of PI3Kδ in the human immune system.Semantic proximity
The T-cell-receptor signaling networkSemantic proximity
The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic DiseasesSemantic proximity
The essential role of phosphoinositide 3-kinases (PI3Ks) in regulating pro-inflammatory responses and the progression of cancer.Semantic proximity
Select a neighboring publication to make it the new centre.