Article

LCK Function and Modulation: Immune Cytotoxic Response and Tumor Treatment. More than a Simple Event.

2024-07-04

Abstract excerpt

LCK, a member of the Scr kinase family, is a non-receptor tyrosine kinase involved in immune cell activation, antigen recognition, tumor growth, and cytotoxic response. The enzyme has usually been linked to T lymphocyte activation upon antigen recognition. Lck activation is central to CD4, CD8, and NK activation. However, recently, it has become clearer that activating the enzyme in CD8 cells can be independent of...

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Literature Corpus work: 76da691e-4c93-565b-a549-16e9ab89d4f5
DOI: 10.20944/preprints202407.0418.v1

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