Article
A recombinant human immunoglobulin with coherent avidity to hepatitis B virus surface antigens of various viral genotypes and clinical mutants.
PloS one - 1 Jan 2020
Jeong Gi Uk, Ahn Byung-Yoon, Jung Jaesung, Kim Hyunjin, Kim Tae-Hee, Kim Woohyun, Lee Ara, Lee Kyuhyun, Kim Jung-Hwan
Abstract excerpt
The hepatitis B virus (HBV) envelope is composed of a lipid bilayer and three glycoproteins, referred to as the large (L), middle (M), and small (S) hepatitis B virus surface antigens (HBsAg). S protein constitutes the major portion of the viral envelope and an even greater proportion of subviral particles (SVP) that circulate in the blood. Recombinant S proteins are currently used as a preventive vaccine, while...
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