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Article

Hybrid large hepatitis B surface protein composed of two viral genotypes C and D induces strongly cross-neutralizing antibodies.

Vaccine - 13 Oct 2023

Sanada Takahiro, Oda Yasunori, Ohashi Chinatsu, Isotani Kentaro, Goh Yasumasa, Kohara Michinori

Abstract excerpt

Hepatitis B virus (HBV) vaccination is known to effectively decrease the risk of HBV infection. However, several issues need to be addressed in order to develop an improved HBV vaccine. Although the HBV vaccine has been shown to be effective, this vaccine needs to be more efficacious in defined groups, including non-responders (i.e., individuals who do not develop a protective response even after vaccination) and...

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Identifiers

PMID: 37739886
DOI: 10.1016/j.vaccine.2023.09.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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