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Article

Monoclonal antibodies to various epitopes of hepatitis B surface antigen inhibit hepatitis B virus infection.

Journal of gastroenterology and hepatology - 1 May 2014

Golsaz Shirazi Forough, Mohammadi Hamed, Amiri Mohammad Mehdi, Singethan Katrin, Xia Yuchen, Bayat Ali Ahmad, Bahadori Motahareh, Rabbani Hodjatallah, Jeddi-Tehrani Mahmood, Protzer Ulrike, Shokri Fazel

Abstract excerpt

BACKGROUND AND AIM: Antibodies against the "a" determinant of hepatitis B surface antigen (HBsAg) are able to neutralize circulating hepatitis B virus (HBV) particles and prevent HBV infection. It has been proposed that a single amino acid exchange may allow the virus to escape the immune response. We used a set of monoclonal antibodies (MAbs) to investigate whether a single mutation may account for virus escape...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24325676
DOI: 10.1111/jgh.12483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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