Clinical implications of hepatitis B virus envelope protein variation.

doi:10.1007/BF02593904

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Article

Clinical implications of hepatitis B virus envelope protein variation.

International journal of clinical & laboratory research - 1 Jan 1994

Wallace L A, Carman W F

Abstract excerpt

The envelope proteins of hepatitis B virus are highly conserved. They are involved in viral attachment to hepatocytes, virion assembly and secretion and induction of humoral and T-cell immune responses. The major neutralisation epitope is located within the S protein and is conformation dependent...

Topics

Amino Acid Sequence
Animals
Antibodies, Viral
Genes, Viral
Genetic Variation
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B Vaccines
Humans
Molecular Sequence Data
Protein Precursors
Vaccination
Viral Envelope Proteins

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