Article
Clinical implications of hepatitis B virus envelope protein variation.
International journal of clinical & laboratory research - 1 Jan 1994
Wallace L A, Carman W F
Abstract excerpt
The envelope proteins of hepatitis B virus are highly conserved. They are involved in viral attachment to hepatocytes, virion assembly and secretion and induction of humoral and T-cell immune responses. The major neutralisation epitope is located within the S protein and is conformation dependent, probably due to the formation of disulphide bridges. Variation in the envelope proteins of hepatitis B virus has been...
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