Article
What factors determine the number of nonmuscle myosin II in the sarcomeric unit of stress fibers?
Biomechanics and modeling in mechanobiology - 1 Feb 2021
Saito Takumi, Huang Wenjing, Matsui Tsubasa S, Kuragano Masahiro, Takahashi Masayuki, Deguchi Shinji
Abstract excerpt
Actin stress fibers (SFs), a contractile apparatus in nonmuscle cells, possess a contractile unit that is apparently similar to the sarcomere of myofibrils in muscles. The function of SFs has thus often been addressed based on well-characterized properties of muscles. However, unlike the fixed number of myosin molecules in myofibrils, the number of nonmuscle myosin II (NMII) within the contractile sarcomeric unit...
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