Article

Myosin Post-translational Modifications Associated with Critical Illness Myopathy

2025-08-25

Abstract excerpt

<h4>Background</h4> Critical Illness Myopathy (CIM) is a devastating consequence of modern critical care, causing dramatic loss of muscle mass and function in intensive care unit (ICU) patients. However, the loss in function by far exceeds the loss in muscle mass and myosin content, but the molecular mechanisms underlying the loss of force and myosin-expressing non-force (NF) generating fibers remain elusive. <h4...

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Literature Corpus work: 8c56f2b0-3687-5894-bdb3-789ad405999a
DOI: 10.1101/2025.08.18.25333907

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