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Article

Cyclic stretch reveals a mechanical role for intermediate filaments in a desminopathic cell model.

Physical biology - 1 Feb 2013

Leccia E, Batonnet-Pichon S, Tarze A, Bailleux V, Doucet J, Pelloux M, Delort F, Pizon V, Vicart P, Briki F

Abstract excerpt

Mechanics is now recognized as crucial in cell function. To date, the mechanical properties of cells have been inferred from experiments which investigate the roles of actin and microtubules ignoring the intermediate filaments (IFs) contribution. Here, we analyse myoblasts behaviour in the context of myofibrillar myopathy resulting from p.D399Y desmin mutation which disorganizes the desmin IF network in muscle...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23234811
DOI: 10.1088/1478-3975/10/1/016001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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