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Article

Polygenic risk score as clinical utility in psychiatry: a clinical viewpoint.

Journal of human genetics - 1 Jan 2021

Ikeda Masashi, Saito Takeo, Kanazawa Tetsufumi, Iwata Nakao

Abstract excerpt

Genome-wide association studies (GWASs) have detected many susceptible variants for common diseases, including psychiatric disorders. However, because of the small effect size of each variant, clinical utility that aims for risk prediction and/or diagnostic assistance based on the individual "variants" is difficult to use. Therefore, to improve the statistical power, polygenic risk score (PRS) has been...

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PMID: 32770057
DOI: 10.1038/s10038-020-0814-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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