Article
A current snapshot of common genomic variants contribution in psychiatric disorders.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2016
Santoro Marcos L, Moretti Patricia N, Pellegrino Renata, Gadelha Ary, Abílio Vanessa C, Hayashi Mirian A F, Belangero Sintia I, Hakonarson Hakon
Abstract excerpt
In the past decade, numerous advances were achieved in psychiatric genetics. Particularly, the genome wide association studies (GWAS) have contributed to uncovering new genes and pathways associated to psychiatric disorders (PDs). At the same time, with increasing sample sizes in the GWAS, the polygenic risk score (PRS) promoted an additional tool for identification and evaluation the genetic risk quantitatively...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
