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Article

A functional missense variant in ITIH3 affects protein expression and neurodevelopment and confers schizophrenia risk in the Han Chinese population.

Journal of genetics and genomics = Yi chuan xue bao - 20 May 2020

Li Kaiqin, Li Yifan, Wang Junyang, Huo Yongxia, Huang Di, Li Shiwu, Liu Jiewei, Li Xiaoyan, Liu Rong, Chen Xiaogang, Yao Yong-Gang, Chen Ceshi, Xiao Xiao, Li Ming, Luo Xiong-Jian

Abstract excerpt

The Psychiatric Genomics Consortium (PGC) has recently identified 10 potential functional coding variants for schizophrenia. However, how these coding variants confer schizophrenia risk remains largely unknown. Here, we investigate the associations between eight potential functional coding variants identified by PGC and schizophrenia in a large Han Chinese sample (n = 4022 cases and 9270 controls). Among the...

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Identifiers

PMID: 32712163
DOI: 10.1016/j.jgg.2020.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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