Article
ITIH family genes confer risk to schizophrenia and major depressive disorder in the Han Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2014
He Kuanjun, Wang Qingzhong, Chen Jianhua, Li Tao, Li Zhiqiang, Li Wenjin, Wen Zujia, Qiang Yu, Wang Meng, Shen Jiawei, Song Zhijian, Ji Jue, Feng Guoyin, Qi Shuguang, Lin He, Shi Yongyong, Cheng Zaohuo
Abstract excerpt
As a major extracellular matrix component, ITIHs played an important role in inflammation and carcinogenesis. Several genome-wide association studies have reported that some positive signals which were derived from the tight linkage disequilibrium region on chromosome 3p21 were associated with both schizophrenia and bipolar disorders in the Caucasian population. To further investigate whether this genomic region...
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