Article
Polymorphism at rs9264942 is associated with HLA-C expression and inflammatory bowel disease in the Japanese.
Scientific reports - 24 Jul 2020
Suzuki Hiroshi, Joshita Satoru, Hirayama Atsuhiro, Shinji Akihiro, Mukawa Kenji, Sako Minako, Yoshimura Naoki, Suga Tomoaki, Umemura Takeji, Ashihara Norihiro, Yamazaki Tomoo, Ota Masao
Abstract excerpt
An expression quantitative trait locus (eQTL) single-nucleotide polymorphism (SNP) at rs9264942 was earlier associated with human leukocyte antigen (HLA)-C expression in Europeans. HLA-C has also been related to inflammatory bowel disease (IBD) risk in the Japanese. This study examined whether an eQTL SNP at rs9264942 could regulate HLA-C expression and whether four SNP haplotypes, including the eQTL SNP at...
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