Article
Genetic Analysis of Ulcerative Colitis in Japanese Individuals Using Population-specific SNP Array.
Inflammatory bowel diseases - 17 Jul 2020
Okamoto Daisuke, Kawai Yosuke, Kakuta Yoichi, Naito Takeo, Torisu Takehiro, Hirano Atsushi, Umeno Junji, Fuyuno Yuta, Li Dalin, Nakano Takeru, Izumiyama Yasuhiro, Ichikawa Ryo, Hiramoto Keiichiro, Moroi Rintaro, Kuroha Masatake, Kanazawa Yoshitake, Shiga Hisashi, Tokunaga Katsushi, Nakamura Minoru, Esaki Motohiro, Matsumoto Takayuki, McGovern Dermot P B, Nagasaki Masao, Kinouchi Yoshitaka, Masamune Atsushi
Abstract excerpt
BACKGROUND: To clarify the genetic background of ulcerative colitis (UC) in the Japanese population, we conducted a genome-wide association study (GWAS) using a population-specific single nucleotide polymorphism (SNP) array. METHODS: We performed a GWAS and replication study including 1676 UC patients and 2381 healthy controls. The probability of colectomy was compared between genotypes of rs117506082, the top...
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