Article
Association of HLA-G 3' Untranslated Region Polymorphisms with Systemic Lupus Erythematosus in a Japanese Population: A Case-Control Association Study.
PloS one - 1 Jan 2016
Hachiya Yuki, Kawasaki Aya, Oka Shomi, Kondo Yuya, Ito Satoshi, Matsumoto Isao, Kusaoi Makio, Amano Hirofumi, Suda Akiko, Setoguchi Keigo, Nagai Tatsuo, Shimada Kota, Sugii Shoji, Okamoto Akira, Chiba Noriyuki, Suematsu Eiichi, Ohno Shigeru, Katayama Masao, Kono Hajime, Hirohata Shunsei, Takasaki Yoshinari, Hashimoto Hiroshi, Sumida Takayuki, Nagaoka Shouhei, Tohma Shigeto, Furukawa Hiroshi, Tsuchiya Naoyuki
Abstract excerpt
HLA-G plays a role in fetal-maternal tolerance as well as immunoregulation, and has been suggested to be involved in autoimmune diseases and cancers. HLA-G encodes two potentially functional polymorphisms in the 3' untranslated region, 14bp insertion/deletion (14bp indel, rs371194629) and a single nucleotide polymorphism rs1063320, previously reported to affect HLA-G expression level or splicing isoform and to be...
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