Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Intergenic Variant rs9268877 Between HLA-DRA and HLA-DRB Contributes to the Clinical Course and Long-term Outcome of Ulcerative Colitis.

Journal of Crohn's & colitis - 29 Aug 2018

Lee Ho-Su, Yang Suk-Kyun, Hong Myunghee, Jung Seulgi, Kim Byoung Mok, Moon Jung Won, Park Sang Hyoung, Ye Byong Duk, Oh Seak Hee, Kim Kyung Mo, Yoon Yong Sik, Yu Chang Sik, Baek Jiwon, Lee Cue Hyunkyu, Han Buhm, Liu Jianjun, Haritunians Talin, McGovern Dermot P B, Song Kyuyoung

Abstract excerpt

BACKGROUND AND AIMS: The genetic contribution to the prognosis of ulcerative colitis [UC] is poorly understood, and most currently known susceptibility loci are not associated with prognosis. To identify genetic variants influencing the prognosis of UC, we performed an Immunochip-based study using an extreme phenotype approach. METHODS: Based on the finding that the only association, Pdiscovery-meta <1 × 10-4,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Prognosis

Source

Identifiers

PMID: 29905830
DOI: 10.1093/ecco-jcc/jjy080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Intergenic Variant rs9268877 Between HLA-DRA and HLA-DRB Contributes to the Clinical Course and Long-term Outcome of Ulcerative Colitis.PMID 29905830Read ↗

HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.Semantic proximity Read ↗

HLA-DRB1*01:03 in patients with inflammatory bowel disease: a genotype-phenotype association study.Semantic proximity Read ↗

An extremes of phenotype approach confirms significant genetic heterogeneity in patients with ulcerative colitisSemantic proximity Read ↗

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.Semantic proximity Read ↗

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.Semantic proximity Read ↗

Amino acid position 11 of HLA-DRβ1 is a major determinant of chromosome 6p association with ulcerative colitis.Semantic proximity Read ↗

Review article: the genetics of the human leucocyte antigen region in inflammatory bowel diseaseSemantic proximity Read ↗

The contribution of human leucocyte antigen complex genes to disease phenotype in ulcerative colitis.Semantic proximity Read ↗

Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associationsSemantic proximity Read ↗

Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations.Semantic proximity Read ↗

Genome-wide analysis of individual coding variants and HLA-II-associated self-immunopeptidomes in ulcerative colitisSemantic proximity Read ↗

The contribution of HLA genes to IBD susceptibility and phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.