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Article

Deoxyribonucleotide pools as targets for mutagenesis by N-methyl-N-nitrosourea.

Mutation research - 1 Jan 2000

Arecco A, Mun B J, Mathews C K

Abstract excerpt

This paper describes a biological test of the hypothesis that one or more components of the intracellular nucleotide pool represent a significant target for the mutagenic effects of alkylating agents. In other words, we ask whether mutagenesis can occur either through alkylation of susceptible nucleotide residues in DNA, or through alkylation of a free nucleotide, followed by its incorporation into DNA. Our...

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PMID: 3260658
DOI: 10.1016/0027-5107(88)90079-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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