Article
Deoxynucleoside triphosphate pool perturbation is not a general feature in mutagen-treated mammalian cells.
Mutation research - 1 Jan 2000
Snyder R D, Davis G F
Abstract excerpt
Deoxynucleoside triphosphate (dNTP) and ribonucleoside triphosphate (rNTP) pools were analyzed in 4 mammalian cell lines following treatment with UV-C (254 nm), UV-A (365 nm) or the carcinogen, 1-methyl-3-nitro-1-nitrosoguanidine (MNNG). No substantial alterations in dNTP pool levels were observed in any treatment group. However, the cellular conversions of exogenously added deoxycytidine and deoxyguanosine to...
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