Consequences of the depletion of cellular deoxynucleoside triphosphate pools on the excision-repair process in cultured human fibroblasts.

doi:10.1016/0027-5107(88)90082-6

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Article

Consequences of the depletion of cellular deoxynucleoside triphosphate pools on the excision-repair process in cultured human fibroblasts.

Mutation research - 1 Jan 2000

Snyder R D

Abstract excerpt

DNA excision repair requires the insertion of bases into gaps in the DNA which arise during the removal of damaged sites from the chromatin. The number of bases required is dependent on the amount of damage and the patch size of repair in response to the particular type of damage. In cells in whi...

Topics

Cells, Cultured
DNA Repair
Deoxyribonucleotides
Humans
Hydroxyurea
Mutation
Purines
Ribonucleotide Reductases
Ultraviolet Rays

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