How MHCII signaling promotes benign host-microbiota interactions

Abstract excerpt

Introduction: Major histocompatibility complex class II molecules and the microbiotaThe major histocompatibility complex (MHC) is a hyper-polymorphic gene-dense region found on Chromosome 6 in humans (the human MHC is termed the HLA for "human leukocyte antigen").The "hyper"-polymorphic nature of this region stems from the extreme allelic diversity found within classical Class I and class II MHC (MHCII) genes [1]...

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