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Article

MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection.

Nature communications - 23 Oct 2015

Kubinak Jason L, Stephens W Zac, Soto Ray, Petersen Charisse, Chiaro Tyson, Gogokhia Lasha, Bell Rickesha, Ajami Nadim J, Petrosino Joseph F, Morrison Linda, Potts Wayne K, Jensen Peter E, O'Connell Ryan M, Round June L

Abstract excerpt

The presentation of protein antigens on the cell surface by major histocompatibility complex (MHC) molecules coordinates vertebrate adaptive immune responses, thereby mediating susceptibility to a variety of autoimmune and infectious diseases. The composition of symbiotic microbial communities (the microbiota) is influenced by host immunity and can have a profound impact on host physiology. Here we use an MHC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26494419
DOI: 10.1038/ncomms9642
PMCID: PMC4621775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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