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Article

Revisiting nonclassical HLA II functions in antigen presentation: Peptide editing and its modulation.

HLA - 1 Oct 2020

Álvaro-Benito Miguel, Freund Christian

Abstract excerpt

The nonclassical major histocompatibility complex of class II molecules (ncMHCII) HLA-DM (DM) and HLA-DO (DO) feature essential functions for the selection of the peptides that are displayed by classical MHCII proteins (MHCII) for CD4+ Th cell surveillance. Thus, although the binding groove of classical MHCII dictates the main features of the peptides displayed, ncMHCII function defines the preferential loading...

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Identifiers

PMID: 32767512
DOI: 10.1111/tan.14007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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