Article
Human MHC architecture and evolution: implications for disease association studies.
International journal of immunogenetics - 1 Jun 2008
Traherne J A
Abstract excerpt
Major histocompatibility complex (MHC) variation is a key determinant of susceptibility and resistance to a large number of infectious, autoimmune and other diseases. Identification of the MHC variants conferring susceptibility to disease is problematic, due to high levels of variation and linkage disequilibrium. Recent cataloguing and analysis of variation over the complete MHC has facilitated localization of...
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