Article
Large-scale genome-wide association study identifies HLA class II variants associated with chronic HBV infection: a study from Taiwan Biobank.
Alimentary pharmacology & therapeutics - 1 Aug 2020
Huang Yu-Han, Liao Shu-Fen, Khor Seik-Soon, Lin Yu-Ju, Chen Hsuan-Yu, Chang Ya-Hsuan, Huang Yi-Hsiang, Lu Sheng-Nan, Lee Hye-Won, Ko Wen-Ya, Huang Claire, Liu Po-Chun, Chen Yen-Ju, Wu Ping-Feng, Chu Hou-Wei, Wu Pei-Ei, Tokunaga Katsushi, Shen Chen-Yang, Lee Mei-Hsuan
Abstract excerpt
BACKGROUND: Chronic hepatitis B virus (HBV) infection is a great health burden with geographical variations. AIMS: To explore genetic variants associated with chronic HBV infection. METHODS: The study included 15 352 participants seropositive for HBV core antibodies in Taiwan Biobank. Among them, 2591 (16.9%) seropositive for HBV surface antigen (HBsAg) were defined as having chronic HBV infection. All...
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