Article
Association between HLA variations and chronic hepatitis B virus infection in Saudi Arabian patients.
PloS one - 1 Jan 2014
Al-Qahtani Ahmed A, Al-Anazi Mashael R, Abdo Ayman A, Sanai Faisal M, Al-Hamoudi Waleed, Alswat Khalid A, Al-Ashgar Hamad I, Khalaf Nisreen Z, Eldali Abdelmoneim M, Viswan Nisha A, Al-Ahdal Mohammed N
Abstract excerpt
Hepatitis B virus (HBV) infection is a leading cause of liver diseases including cirrhosis and hepatocellular carcinoma. Human leukocyte antigens (HLAs) play an important role in the regulation of immune response against infectious organisms, including HBV. Recently, several genome-wide association (GWAS) studies have shown that genetic variations in HLA genes influence disease progression in HBV infection. The...
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