Article
Clinical Relevance of HLA Gene Variants in HBV Infection.
Journal of immunology research - 1 Jan 2016
Wang Li, Zou Zhi-Qiang, Wang Kai
Abstract excerpt
Host gene variants may influence the natural history of hepatitis B virus (HBV) infection. The human leukocyte antigen (HLA) system, the major histocompatibility complex (MHC) in humans, is one of the most important host factors that are correlated with the clinical course of HBV infection. Genome-wide association studies (GWASs) have shown that single nucleotide polymorphisms (SNPs) near certain HLA gene loci...
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