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Exploratory analysis of HLA variants and occult HBV infection: a multicenter case-control study in Chinese blood donors

2025-09-01

Abstract excerpt

<title>Abstract</title> <p>Occult hepatitis B virus infection (OBI), characterized by detectable HBV DNA but undetectable HBsAg, poses diagnostic and clinical challenges, with host genetic factors, particularly HLA-mediated immune regulation, remaining poorly understood. Through whole-exome sequencing of 147 participants (74 OBI cases, 73 chronic HBsAg+ controls), we identified four HLA variants associated with l...

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Literature Corpus work
3176e520-ad03-52e1-86fb-f641a0f455bb
DOI
10.21203/rs.3.rs-7323223/v1
Open publication

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Exploratory analysis of HLA variants and occult HBV infection: a multicenter case-control study in Chinese blood donorsDOI 10.21203/rs.3.rs-7323223/v1
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