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Article

A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese.

PloS one - 1 Jan 2014

Chang Su-Wei, Fann Cathy Shen-Jang, Su Wen-Hui, Wang Yu Chen, Weng Chia Chan, Yu Chia-Jung, Hsu Chia-Lin, Hsieh Ai-Ru, Chien Rong-Nan, Chu Chia-Ming, Tai Dar-In

Abstract excerpt

It is common to observe the clustering of chronic hepatitis B surface antigen (HBsAg) carriers in families. Intra-familial transmission of hepatitis B virus (HBV) could be the reason for the familial clustering of HBsAg carriers. Additionally, genetic and gender factors have been reported to be involved. We conducted a three-stage genome-wide association study to identify genetic factors associated with chronic...

Topics

Disease Progression
Ethnicity
Genome-Wide Association Study
Haplotypes
Hepatitis B Surface Antigens
Hepatitis B, Chronic
Humans
Linkage Disequilibrium
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Reproducibility of Results

Taiwan

Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 24940741
DOI: 10.1371/journal.pone.0099724
PMCID: PMC4062466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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