Article
New loci associated with chronic hepatitis B virus infection in Han Chinese.
Nature genetics - 1 Dec 2013
Hu Zhibin, Liu Yao, Zhai Xiangjun, Dai Juncheng, Jin Guangfu, Wang Li, Zhu Liguo, Yang Yuan, Liu Jibin, Chu Minjie, Wen Juan, Xie Kaipeng, Du Guoming, Wang Qungang, Zhou Yuchun, Cao Minquan, Liu Li, He Yisha, Wang Ying, Zhou Gangqiao, Jia Weihua, Lu Jiachun, Li Shengping, Liu Jianjun, Yang Haitao, Shi Yongyong, Zhou Weiping, Shen Hongbing
Abstract excerpt
Chronic hepatitis B virus (HBV) infection is a challenging global health problem. To identify genetic loci involved in chronic HBV infection, we designed a three-phase genome-wide association study in Han Chinese populations. The discovery phase included 951 HBV carriers (cases) and 937 individuals who had naturally cleared HBV infection (controls) and was followed by independent replications with a total of...
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