Article
Host genetic factors affecting hepatitis B infection outcomes: Insights from genome-wide association studies.
World journal of gastroenterology - 14 Aug 2018
Akcay Izzet Mehmet, Katrinli Seyma, Ozdil Kamil, Doganay Gizem Dinler, Doganay Levent
Abstract excerpt
The clinical outcome of hepatitis B virus (HBV) infection depends on the success or failure of the immune responses to HBV, and varies widely among individuals, ranging from asymptomatic self-limited infection, inactive carrier state, chronic hepatitis, cirrhosis, hepatocellular carcinoma, to liver failure, depending on the success or failure of immune response to HBV. Genome-wide association studies (GWAS)...
Topics
- Alleles
- Antigen Presentation
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- HLA Antigens
- Hepatitis B
- Hepatitis B Vaccines
- Hepatitis B virus
- Humans
- Immunogenicity, Vaccine
- Polymorphism, Single Nucleotide
- Precision Medicine