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Article

Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population.

Genetics and molecular research : GMR - 31 May 2017

Pereira V R Z B, Wolf J M, Stumm G Z, Boeira T R, Galvan J, Simon D, Lunge V R

Abstract excerpt

Hepatitis B virus (HBV) infection is a serious public health problem worldwide. The progression of the disease depends on several host and viral factors and may result in fulminant hepatitis (very rare), acute hepatitis with spontaneous clearance, and chronic hepatitis B infection. Previous studies demonstrated that variations in the human leukocyte antigen (HLA) class II (HLA-DPB1 and HLA-DQB2 genes) are related...

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PMID: 28613373
DOI: 10.4238/gmr16029565

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