Article

Efficient Human Germ Cell Specification from Stem Cells via Combinatorial Expression of Transcription Factors

2022-07-12

Abstract excerpt

Germ cells are the vehicle of human reproduction, arising early in embryonic development and developing throughout adult life until menopause onset in women. Primordial germ cells are the common precursors of germline cells in both sexes, undergoing sexual specification into oogonia or gonocytes which further develop into oocytes or spermatocytes during development. Methods for recapitulation of primordial germ ce...

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Literature Corpus work: 5247fa61-ca90-53bd-bcf8-e26a8bb3e3d3
DOI: 10.1101/2022.07.11.499564

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