Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Absence of SCAPER causes male infertility in humans and Drosophila by modulating microtubule dynamics during meiosis.

Journal of medical genetics - 1 Apr 2021

Wormser Ohad, Levy Ygal, Bakhrat Anna, Bonaccorsi Silvia, Graziadio Lucia, Gatti Maurizio, AbuMadighem Ali, McKenney Richard J, Okada Kyoko, El Riati Saad, Har-Vardi Iris, Huleihel Mahmoud, Levitas Eliahu, Birk Ohad S, Abdu Uri

Abstract excerpt

BACKGROUND: Mutation in S-phase cyclin A-associated protein rin the endoplasmic reticulum (SCAPER) have been found across ethnicities and have been shown to cause variable penetrance of an array of pathological traits, including intellectual disability, retinitis pigmentosa and ciliopathies. METHODS: Human clinical phenotyping, surgical testicular sperm extraction and testicular tissue staining. Generation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Segregation
Share to Infertility, Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Meiosis

Share to Microtubules

Share to Serine Endopeptidases

Share to Spermatocytes

Share to Spindle Apparatus

Share to Testis

Source

Open in PubMed Open full text

Identifiers

PMID: 32527956
DOI: 10.1136/jmedgenet-2020-106946
PMCID: PMC10405349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Absence of SCAPER causes male infertility in humans and Drosophila by modulating microtubule dynamics during meiosis.PMID 32527956Read ↗

STAG3 is a strong candidate gene for male infertilitySemantic proximity Read ↗

Loss of TDP-43 in male germ cells causes meiotic failure and impairs fertility in miceSemantic proximity Read ↗

The sperm centrosome during fertilization in mammals: implications for fertility and reproductionSemantic proximity Read ↗

New allele of mouse DNA/RNA helicase senataxin causes meiotic arrest and infertility.Semantic proximity Read ↗

SEPT12/SPAG4/LAMINB1 Complexes Are Required for Maintaining the Integrity of the Nuclear Envelope in Postmeiotic Male Germ CellsSemantic proximity Read ↗

The conserved kinase SRPK regulates karyosome formation and spindle microtubule assembly in Drosophila oocytes.Semantic proximity Read ↗

GOLPH3 is essential for contractile ring formation and Rab11 localization to the cleavage site during cytokinesis in Drosophila melanogaster.Semantic proximity Read ↗

Aurora B and C kinases regulate prophase exit and chromosome segregation during spermatogenesisSemantic proximity Read ↗

The roles of fission yeast ase1 in mitotic cell division, meiotic nuclear oscillation, and cytokinesis checkpoint signaling.Semantic proximity Read ↗

Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3.Semantic proximity Read ↗

Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation.Semantic proximity Read ↗

Mouse Embryonic Stem Cells Form Follicle‐Like Ovarian Structures but Do Not Progress Through MeiosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.