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Article

STAG3 is a strong candidate gene for male infertility

7 Mar 2014

Abstract excerpt

Oligo- and azoospermia are severe forms of male infertility. However, known genetic factors account only for a small fraction of the cases. Recently, whole-exome sequencing in a large consanguineous family with inherited premature ovarian failure (POF) identified a homozygous frameshift mutation in the STAG3 gene leading to a premature stop codon. STAG3 encodes a meiosis-specific subunit of the cohesin complex, a...

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Identifiers

PMID: 24608227
DOI: 10.1093/hmg/ddu051

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STAG3 is a strong candidate gene for male infertilityPMID 24608227Read ↗

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