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SEPT12/SPAG4/LAMINB1 Complexes Are Required for Maintaining the Integrity of the Nuclear Envelope in Postmeiotic Male Germ Cells

16 Mar 2015

Abstract excerpt

Male infertility affects approximately 50% of all infertile couples. The male-related causes of intracytoplasmic sperm injection failure include the absence of sperm, immotile or immature sperm, and sperm with structural defects such as those caused by premature chromosomal condensation and DNA damage. Our previous studies based on a knockout mice model indicated that SEPT12 proteins are critical for the terminal...

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PMID: 25775403
DOI: 10.1371/journal.pone.0120722

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SEPT12/SPAG4/LAMINB1 Complexes Are Required for Maintaining the Integrity of the Nuclear Envelope in Postmeiotic Male Germ CellsPMID 25775403Read ↗

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SUN5 Interacting With Nesprin3 Plays an Essential Role in Sperm Head-to-Tail Linkage: Research on Sun5 Gene Knockout MiceSemantic proximity Read ↗

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Homozygous Loss of Septin12, but not its Haploinsufficiency, Leads to Male Infertility and Fertilization FailureSemantic proximity Read ↗

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