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Mouse Embryonic Stem Cells Form Follicle‐Like Ovarian Structures but Do Not Progress Through Meiosis

28 Apr 2006

Abstract excerpt

Several recent studies have suggested that mouse embryonic stem cells (ESCs) can differentiate into female and male germ cells in vitro. The meiotic process in germ cell-like cells derived from ESCs has not been studied in detail, but it has been reported that synaptonemal complex protein-3 (SYCP3) is expressed in these cells. Here, we have carefully evaluated the meiotic process in germ cell-like cells derived...

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PMID: 16644921
DOI: 10.1634/stemcells.2005-0520

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