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Article

Misactivation of multiple starvation responses in yeast by loss of tRNA modifications.

Nucleic acids research - 27 Jul 2020

Bruch Alexander, Laguna Teresa, Butter Falk, Schaffrath Raffael, Klassen Roland

Abstract excerpt

Previously, combined loss of different anticodon loop modifications was shown to impair the function of distinct tRNAs in Saccharomyces cerevisiae. Surprisingly, each scenario resulted in shared cellular phenotypes, the basis of which is unclear. Since loss of tRNA modification may evoke transcriptional responses, we characterized global transcription patterns of modification mutants with defects in either...

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Identifiers

PMID: 32484543
DOI: 10.1093/nar/gkaa455
PMCID: PMC7367188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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