Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptome-wide Analysis of Roles for tRNA Modifications in Translational Regulation.

Molecular cell - 7 Dec 2017

Chou Hsin-Jung, Donnard Elisa, Gustafsson H Tobias, Garber Manuel, Rando Oliver J

Abstract excerpt

Covalent nucleotide modifications in noncoding RNAs affect a plethora of biological processes, and new functions continue to be discovered even for well-known modifying enzymes. To systematically compare the functions of a large set of noncoding RNA modifications in gene regulation, we carried out ribosome profiling in budding yeast to characterize 57 nonessential genes involved in tRNA modification. Deletion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic-Leucine Zipper Transcription Factors
Share to Retroelements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ribosomes

Share to RNA, Fungal

Share to RNA, Transfer

Share to RNA, Untranslated

Share to Terminal Repeat Sequences

Share to tRNA Methyltransferases

Source

Open in PubMed Open full text

Identifiers

PMID: 29198561
DOI: 10.1016/j.molcel.2017.11.002
PMCID: PMC5728682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptome-wide Analysis of Roles for tRNA Modifications in Translational Regulation.PMID 29198561Read ↗

tModBase: deciphering the landscape of tRNA modifications and their dynamic changes from epitranscriptome dataSemantic proximity Read ↗

Modify or die?--RNA modification defects in metazoans.Semantic proximity Read ↗

Biosynthesis and function of posttranscriptional modifications of transfer RNAs.Semantic proximity Read ↗

tRNA modifications: greasing the wheels of translation and beyondSemantic proximity Read ↗

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosaSemantic proximity Read ↗

snoRNA-guided tRNA 2’-O-methylation controls codon-biased gene expression and cellular statesSemantic proximity Read ↗

Loss of Conserved rRNA Modifications in the Peptidyl Transferase Center Leads to Diminished Protein Synthesis and Cell Growth in Budding Yeast.Semantic proximity Read ↗

Systematic identification of factors mediating accelerated mRNA degradation in response to changes in environmental nitrogen.Semantic proximity Read ↗

Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responsesSemantic proximity Read ↗

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and functionSemantic proximity Read ↗

A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growthSemantic proximity Read ↗

A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.