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Article

HotSpotAnnotations-a database for hotspot mutations and annotations in cancer.

Database : the journal of biological databases and curation - 1 Jan 2020

Trevino Victor

Abstract excerpt

Hotspots, recurrently mutated DNA positions in cancer, are thought to be oncogenic drivers because random chance is unlikely and the knowledge of clear examples of oncogenic hotspots in genes like BRAF, IDH1, KRAS and NRAS among many other genes. Hotspots are attractive because provide opportunities for biomedical research and novel treatments. Nevertheless, recent evidence, such as DNA hairpins for APOBEC3A,...

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Identifiers

PMID: 32386297
DOI: 10.1093/database/baaa025
PMCID: PMC7211031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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