Article

Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instability

2020-10-16

Abstract excerpt

<h4>Background</h4> Genetic variants, underlining phenotypic diversity, are known to distribute unevenly in the human genome. A comprehensive understanding of the distributions of different genetic variants is important for insights into genetic functions and disorders. <h4>Methods</h4> Herein, a sliding-window scan of regional densities of eight kinds of germline genetic variants, including single-nucleotide-po...

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Literature Corpus work: 7e51eafc-b082-5c1f-a49b-d831e2194645
DOI: 10.1101/2020.10.16.342188

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