Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CardioHotspots: a database of mutational hotspots for cardiac disorders.

Database : the journal of biological databases and curation - 15 May 2024

García S Alberto, Costa Mireia, García-Zarzoso Alba, Pastor Oscar

Abstract excerpt

Mutational hotspots are DNA regions with an abnormally high frequency of genetic variants. Identifying whether a variant is located in a mutational hotspot is critical for determining the variant's role in disorder predisposition, development, and treatment response. Despite their significance, current databases on mutational hotspots are limited to the oncology domain. However, identifying mutational hotspots is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Genetic
Share to Heart Diseases
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 38752292
DOI: 10.1093/database/baae034
PMCID: PMC11096770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CardioHotspots: a database of mutational hotspots for cardiac disorders.PMID 38752292Read ↗

HotSpotAnnotations-a database for hotspot mutations and annotations in cancer.Semantic proximity Read ↗

Hotspots of Human Mutation.Semantic proximity Read ↗

Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types.Semantic proximity Read ↗

HCSeeker: A classification tool for human genetic variant hot and cold spots designed for PM1 and benign criteria in the ACMG-AMP guideline.Semantic proximity Read ↗

MutSpot: detection of non-coding mutation hotspots in cancer genomesSemantic proximity Read ↗

Pathogenic mutation hotspots in protein kinase domain structure.Semantic proximity Read ↗

Identification of Local Clusters of Mutation Hotspots in Cancer-Related Genes and Their Biological Relevance.Semantic proximity Read ↗

Functional annotation of HOT regions in the human genome: implications for human disease and cancer.Semantic proximity Read ↗

Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instabilitySemantic proximity Read ↗

A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.Semantic proximity Read ↗

SMuRF: a novel tool to identify genomic regions enriched for somatic point mutationsSemantic proximity Read ↗

A full-proteome, interaction-specific characterization of mutational hotspots across human cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.