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Article

The MUC6/AP2A2 Locus and Its Relevance to Alzheimer's Disease: A Review.

Journal of neuropathology and experimental neurology - 1 Jun 2020

Nelson Peter T, Fardo David W, Katsumata Yuriko

Abstract excerpt

We recently reported evidence of Alzheimer's disease (AD)-linked genetic variation within the mucin 6 (MUC6) gene on chromosome 11p, nearby the adaptor-related protein complex 2 subunit alpha 2 (AP2A2) gene. This locus has interesting features related to human genomics and clinical research. MUC6 gene variants have been reported to potentially influence viral-including herpesvirus-immunity and the gut microbiome....

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Source

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Identifiers

PMID: 32357373
DOI: 10.1093/jnen/nlaa024
PMCID: PMC7241941

Genes

AP2A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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